Obesity has increasingly become a major health problem of pandemic proportions. The U.S. CDC reported on June 14 that one in three children born in year 2000 will eventually develop diabetes, mostly type 2 which results largely from obesity and certain life styles. Genetic abnormalities associated with childhood obesity have been reported but remain short of a definitive correlation.
I.S. Farooqi and colleagues from Addenbrooke’s Hospital, Cambridge, UK and R. Branson and colleagues from Klinik Hirslanden, Zurich, Switzerland both reported recently in New England Journal of Medicine (348:1085-1095, 348:1096-1103, March 20, 2003) that a deficiency in melanocortin 4 receptor (MC4R) is ... Read more