Discovery Medicine is endowed with a passion to facilitate a greater utilization of cutting-edge biomedical research information for the advancement of both continued research and patient care. This includes the cross-referencing of important information such as new ideas, technical breakthroughs, and illuminating conclusions among various medical specialties. Non-research physicians and other professionals can quickly obtain the latest information on the new understanding of diseases, new treatment options, and investigational therapies.

Now we are pleased to add non-medically trained, healthcare-conscious individuals to the journal’s audience. Although some articles may be technical in nature and may inevitably use some scientific terms, readers of ... Read more

Abstract: Jamie Heywood's younger brother Stephen was diagnosed with Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's disease). Trying to save his brother, Jamie ventured on a roller-coaster ride right on the edge of medicine. ... Read more

Abstract: Magic bullets armed with nuclear war head? Monoclonal antibodies labeled with radioactive isotope, when taken orally, seek and attach to tumor cells and bring radiation close to a range of destruction. ... Read more

Abstract: Both radiation and DNA topoisomerase I drugs (widely used Camptosar class of drugs) injure or interfere with cell DNA. There appears to be a synergy in killing cancer cells when both are used at the same time. ... Read more

Abstract: Tumor suppresses immune functions. Immunotherapy with self immune cells taken from the body, empowered in petri dishes, and returned to the body remains a valuable means to contain tumor. The procedure for enhancing immune cells outside the body has not been efficient and reliable. Authors described an innovative technology to address the problem. ... Read more

Abstract: Nerve regeneration in brain and spinal cord is suppressed by inhibitory molecules, among other factors, at the injury site. Injection of cyclic AMP, a key cellular signaling molecule, and Schwann cells (a type of nerve cells) to the injury site immediately after the injury helped mice recover from paralysis. ... Read more

Abstract: There have been a number of reports documenting that a much decreased incidence of malignancy has been recorded in populations where infectious diseases are epidemic. This bacteria's unique capability is recruited to fight cancer. ... Read more

Abstract: Upon a tissue injury (infection, for example), a variety of biological mediators trigger an acute inflammatory response, with immune cells and inflammatory molecules answering the call of duty. When the source of the injury is eliminated by this highly active, interactive, and often powerful process, immune agents withdraw and peace stands. When they don't or the source of the injury persists, chronic inflammatory diseases such as arthritis, asthma, and atherosclerosis follow. ... Read more

Abstract: Fresh memories undergo a consolidation process to become permanent. The consolidation process, in which original patterns of synaptic connections (neuron networks) are retrieved and new patterns are formed, is subject to disruption by distracting stimuli, pharmaceutical agents, and toxins, among others. The consolidated memory may, at times, be different from the original one. ... Read more

Abstract: What motivates us to act in a certain way? Motivation is driven by rewards -- the satisfaction of enjoying what we desire. Dopamine is a neurotransmitter whose scarcity causes Parkinson's disease. Recent research revealed that brain dopamine plays a major role for rewards to establish learned response habits and preferences. ... Read more