Articles Authored and/or Co-authored by

William M Pardridge, M.D.


Molecular Trojan Horses for Blood-Brain Barrier Drug Delivery

Abstract: Molecular Trojan horses are genetically engineered proteins that cross the blood-brain barrier (BBB) via endogenous receptor-mediated transport processes. Molecular Trojan horses provide a brain drug targeting technology that allows for the non-invasive delivery of large molecule therapeutics to the human brain. The development of BBB drug targeting technology is an arcane area of discovery medicine that suffers from chronic under-development. ... Read more

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